Properties of Bioactive Glass

Bioactive glass (BAG) is a kind of material that can repair, replace and regenerate body tissues, and has the ability to form bonds between tissues and materials. Discovered by Hench in 1969, BAG is a silicate glass composed of basic components such as SiO2, Na2O, CaO and P2O5. The degradation products of bioactive glass can promote the production of growth factors, promote cell proliferation, enhance the gene expression of osteoblasts and the growth of bone tissue. It is the only artificial biomaterial so far that can bond with bone tissue and connect with soft tissue at the same time.

    The composition of bioactive glass is mainly: SiO2, Na2O, CaO, P2O5 and so on. Bioactive glass ceramics are polycrystals obtained by controlled crystallization on the basis of bioactive glass. Compared with the traditional soda-lime-silicon system glass, it has three major composition characteristics: low SiO2 content; high Na2O and CaO content; high CaO/P2O5 ratio. C. Preparation process: The preparation process of bioactive glass is basically the same as the traditional glass preparation process, including weighing, mixing, fusion, melting, homogenization, glass formation, etc. Glass ceramics also need to control glass nucleation and grain growth under a certain heat treatment system.

    Bioactive glass (BAG) is a silicate glass composed of basic components such as SiO2, Na2O, CaO and P2O5. The most notable feature of bioactive glass and glass ceramics is that after implantation into the human body, the surface condition changes dynamically with time, and a bioactive hydroxycarbonated apatite (HCA) layer is formed on the surface, which provides a bonding interface for the tissue. Most bioactive glass is a class A bioactive material, which has both osteoproductive and osteoconductive effects, and has good bonding with bone and soft tissue. BAG is considered to be applicable in the field of repair. Good biological material. This kind of restorative material is not only widely used, but also has irreplaceable magical effects in professional products in many fields, such as skin care, whitening and wrinkle removal, burns and scalds, oral ulcers, gastrointestinal ulcers, skin ulcers, killing fungi. , bone repair, bonding of soft tissue and bone tissue, etc., it is believed that its emergence will make outstanding contributions to human health. In addition, BAG also has a fast surface reaction; the amorphous two-dimensional structure makes the strength and fracture toughness low; the elastic modulus (30-35MPa) is low, close to cortical bone; the machinable bioglass has good processing performance.